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==A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form==
==A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form==
<StructureSection load='4otk' size='340' side='right' caption='[[4otk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4otk' size='340' side='right'caption='[[4otk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4otk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OTK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4otk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OTK FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4otk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4otk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4otk RCSB], [http://www.ebi.ac.uk/pdbsum/4otk PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4otk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4otk OCA], [https://pdbe.org/4otk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4otk RCSB], [https://www.ebi.ac.uk/pdbsum/4otk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4otk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Y2971_MYCTU Y2971_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form.,Shahine A, Prasetyoputri A, Rossjohn J, Beddoe T Acta Crystallogr F Struct Biol Commun. 2014 May;70(Pt 5):572-7. doi:, 10.1107/S2053230X14007158. Epub 2014 Apr 17. PMID:24817712<ref>PMID:24817712</ref>
A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form.,Shahine A, Prasetyoputri A, Rossjohn J, Beddoe T Acta Crystallogr F Struct Biol Commun. 2014 May;70(Pt 5):572-7. doi:, 10.1107/S2053230X14007158. Epub 2014 Apr 17. PMID:24817712<ref>PMID:24817712</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4otk" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beddoe, T.]]
[[Category: Large Structures]]
[[Category: Shahine, A.]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Oxidoreductase]]
[[Category: Beddoe T]]
[[Category: Tim barrel]]
[[Category: Shahine A]]
Retrieved from "https://proteopedia.org/4otk"