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==Crystal structure of Arginyl-tRNA synthetase complexed with L-arginine==
==Crystal structure of Arginyl-tRNA synthetase complexed with L-arginine==
<StructureSection load='4q2t' size='340' side='right' caption='[[4q2t]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4q2t' size='340' side='right'caption='[[4q2t]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4q2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q2T FirstGlance]. <br>
<table><tr><td colspan='2'>[[4q2t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q2T FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q2x|4q2x]], [[4q2y|4q2y]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RARS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q2t OCA], [https://pdbe.org/4q2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q2t RCSB], [https://www.ebi.ac.uk/pdbsum/4q2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q2t ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine--tRNA_ligase Arginine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.19 6.1.1.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q2t OCA], [http://pdbe.org/4q2t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q2t RCSB], [http://www.ebi.ac.uk/pdbsum/4q2t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q2t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SYRC_HUMAN SYRC_HUMAN]] Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.<ref>PMID:17443684</ref>
[https://www.uniprot.org/uniprot/SYRC_HUMAN SYRC_HUMAN] Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.<ref>PMID:17443684</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4q2t" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4q2t" style="background-color:#fffaf0;"></div>
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arginine--tRNA ligase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Cha, S Y]]
[[Category: Cha SY]]
[[Category: Han, A R]]
[[Category: Han AR]]
[[Category: Hwang, K Y]]
[[Category: Hwang KY]]
[[Category: Jo, C H]]
[[Category: Jo CH]]
[[Category: Kim, H S]]
[[Category: Kim HS]]
[[Category: Arginine binding]]
[[Category: Arginine-trna ligase activity]]
[[Category: High region]]
[[Category: Ligase]]
[[Category: Trna binding]]
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