4r12: Difference between revisions
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<StructureSection load='4r12' size='340' side='right'caption='[[4r12]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='4r12' size='340' side='right'caption='[[4r12]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4r12]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R12 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4r12]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_purpureum Dictyostelium purpureum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R12 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r12 OCA], [https://pdbe.org/4r12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r12 RCSB], [https://www.ebi.ac.uk/pdbsum/4r12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r12 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r12 OCA], [https://pdbe.org/4r12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r12 RCSB], [https://www.ebi.ac.uk/pdbsum/4r12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r12 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NICA_DICPU NICA_DICPU] Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).[UniProtKB:Q92542] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Dictyostelium purpureum]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Lu | [[Category: Lu P]] | ||
[[Category: Ma | [[Category: Ma D]] | ||
[[Category: Shi | [[Category: Shi Y]] | ||
[[Category: Sun | [[Category: Sun L]] | ||
[[Category: Xie | [[Category: Xie T]] | ||
[[Category: Yan | [[Category: Yan C]] | ||
[[Category: Yang | [[Category: Yang G]] | ||
[[Category: Zhao | [[Category: Zhao Y]] | ||
[[Category: Zhou | [[Category: Zhou R]] | ||
Latest revision as of 15:11, 8 November 2023
Crystal structure of the gamma-secretase component Nicastrin
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