3f87: Difference between revisions

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{{Seed}}
[[Image:3f87.png|left|200px]]


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==An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quarternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions - higher symmetry crystal==
The line below this paragraph, containing "STRUCTURE_3f87", creates the "Structure Box" on the page.
<StructureSection load='3f87' size='340' side='right'caption='[[3f87]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3f87]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F87 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=B3L:(3S)-3-AMINO-5-METHYLHEXANOIC+ACID'>B3L</scene>, <scene name='pdbligand=B3M:(3R)-3-AMINO-5-(METHYLSULFANYL)PENTANOIC+ACID'>B3M</scene>, <scene name='pdbligand=BIL:(3R,4S)-3-AMINO-4-METHYLHEXANOIC+ACID'>BIL</scene>, <scene name='pdbligand=HMR:BETA-HOMOARGININE'>HMR</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
{{STRUCTURE_3f87|  PDB=3f87  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f87 OCA], [https://pdbe.org/3f87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f87 RCSB], [https://www.ebi.ac.uk/pdbsum/3f87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f87 ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Helix bundles are among the most widely studied tertiary and quaternary structural motifs in proteins. Here we present the crystal structure of an alpha/beta-peptide foldamer that adopts a tetrameric helix-bundle quaternary structure with a hydrophobic core composed solely of beta-amino acids. The structure displays features that are unprecedented among all known helix bundles composed of either alpha-peptides or peptidic foldamers. The tetramer is characterized by an asymmetry of interaction between neighboring helices, and the side-chain packing within the hydrophobic core differs fundamentally from the knobs-into-holes arrangement typical of most helix bundles.


===An alpha/beta-Peptide Helix Bundle with a Pure beta-Amino Acid Core and a Distinctive Quarternary Structure: GCN4pLI derivative with beta residues at a and d heptad positions - higher symmetry crystal===
An alpha/beta-Peptide Helix Bundle with a Pure beta(3)-Amino Acid Core and a Distinctive Quaternary Structure.,Giuliano MW, Horne WS, Gellman SH J Am Chem Soc. 2009 Jul 6. PMID:19580264<ref>PMID:19580264</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 3f87" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 19580264 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_19580264}}
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</StructureSection>
==About this Structure==
[[Category: Large Structures]]
3F87 is a 4 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F87 OCA].
[[Category: Gellman SH]]
 
[[Category: Giuliano MW]]
==Reference==
[[Category: Horne WS]]
<ref group="xtra">PMID:19580264</ref><references group="xtra"/>
[[Category: Gellman, S H.]]
[[Category: Giuliano, M W.]]
[[Category: Horne, W S.]]
[[Category: Alpha/beta-peptide]]
[[Category: Coiled coil]]
[[Category: Foldamer]]
[[Category: Gcn4 derivative]]
[[Category: Helix bundle]]
[[Category: Unknown function]]
 
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Retrieved from "https://proteopedia.org/3f87"