5wyg: Difference between revisions

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==The crystal structure of the apo form of Mtb MazF==
==The crystal structure of the apo form of Mtb MazF==
<StructureSection load='5wyg' size='340' side='right' caption='[[5wyg]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
<StructureSection load='5wyg' size='340' side='right'caption='[[5wyg]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5wyg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WYG FirstGlance]. <br>
<table><tr><td colspan='2'>[[5wyg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WYG FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wyg OCA], [http://pdbe.org/5wyg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wyg RCSB], [http://www.ebi.ac.uk/pdbsum/5wyg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wyg ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.356&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wyg OCA], [https://pdbe.org/5wyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wyg RCSB], [https://www.ebi.ac.uk/pdbsum/5wyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wyg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MAZF7_MYCTU MAZF7_MYCTU]] Toxic component of a type II toxin-antitoxin (TA) module. Upon expression in E.coli and M.smegmatis inhibits cell growth and colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE7 (PubMed:19016878, PubMed:20011113). Probably an endoribonuclease (By similarity).[UniProtKB:P9WIH9]<ref>PMID:19016878</ref> <ref>PMID:20011113</ref>
[https://www.uniprot.org/uniprot/MAZF7_MYCTU MAZF7_MYCTU] Toxic component of a type II toxin-antitoxin (TA) module. Upon expression in E.coli and M.smegmatis inhibits cell growth and colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE7 (PubMed:19016878, PubMed:20011113). Probably an endoribonuclease (By similarity).[UniProtKB:P9WIH9]<ref>PMID:19016878</ref> <ref>PMID:20011113</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chen, R]]
[[Category: Large Structures]]
[[Category: Tu, J]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Xie, W]]
[[Category: Chen R]]
[[Category: Hydrolase]]
[[Category: Tu J]]
[[Category: Mazf]]
[[Category: Xie W]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Toxin-antitoxin system]]