7ehm: Difference between revisions

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<StructureSection load='7ehm' size='340' side='right'caption='[[7ehm]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
<StructureSection load='7ehm' size='340' side='right'caption='[[7ehm]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7ehm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EHM FirstGlance]. <br>
<table><tr><td colspan='2'>[[7ehm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EHM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J49:(2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic+acid'>J49</scene>, <scene name='pdbligand=J4C:(2S)-2-[[4-[[1-[(3,4-dichlorophenyl)methyl]-3,7-dimethyl-2,6-bis(oxidanylidene)purin-8-yl]amino]phenyl]carbonylamino]pentanedioic+acid'>J4C</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7ehj|7ehj]], [[7ehn|7ehn]], [[7ehv|7ehv]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J49:(2S)-2-[[4-[(4-azanyl-6-oxidanyl-pyrimidin-5-yl)carbamoylamino]phenyl]carbonylamino]pentanedioic+acid'>J49</scene>, <scene name='pdbligand=J4C:(2S)-2-[[4-[[1-[(3,4-dichlorophenyl)methyl]-3,7-dimethyl-2,6-bis(oxidanylidene)purin-8-yl]amino]phenyl]carbonylamino]pentanedioic+acid'>J4C</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTHFD2, NMDMC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ehm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ehm OCA], [https://pdbe.org/7ehm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ehm RCSB], [https://www.ebi.ac.uk/pdbsum/7ehm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ehm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ehm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ehm OCA], [https://pdbe.org/7ehm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ehm RCSB], [https://www.ebi.ac.uk/pdbsum/7ehm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ehm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTDC_HUMAN MTDC_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7ehm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7ehm" style="background-color:#fffaf0;"></div>
==See Also==
*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lee, L C]]
[[Category: Lee LC]]
[[Category: Peng, Y H]]
[[Category: Peng YH]]
[[Category: Wu, S Y]]
[[Category: Wu SY]]
[[Category: 1c metabolism]]
[[Category: Methylenetetrahydrofolate dehydrogenase 2]]
[[Category: Mitocondria]]
[[Category: Mthfd2]]
[[Category: Oxidoreductase]]

Latest revision as of 16:53, 29 November 2023

Human MTHFD2 in complex with compound 21 and 15

7ehm, resolution 2.13Å

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