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{{STRUCTURE_3s19|  PDB=3s19  |  SCENE=  }}
===Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0===


==Function==
==Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0==
[[http://www.uniprot.org/uniprot/QUEF_VIBCH QUEF_VIBCH]] Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity).  
<StructureSection load='3s19' size='340' side='right'caption='[[3s19]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3s19]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S19 FirstGlance]. <br>
[[3s19]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S19 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5009&#8491;</td></tr>
[[Category: Vibrio cholerae]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr>
[[Category: Anderson, W F.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s19 OCA], [https://pdbe.org/3s19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s19 RCSB], [https://www.ebi.ac.uk/pdbsum/3s19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s19 ProSAT]</span></td></tr>
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
</table>
[[Category: Gu, M.]]
== Function ==
[[Category: Joachimiak, A.]]
[https://www.uniprot.org/uniprot/QUEF_VIBCH QUEF_VIBCH] Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity).
[[Category: Kim, Y.]]
__TOC__
[[Category: Zhou, M.]]
</StructureSection>
[[Category: Alpha-beta structure]]
[[Category: Large Structures]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
[[Category: Csgid]]
[[Category: Anderson WF]]
[[Category: Cytosol]]
[[Category: Gu M]]
[[Category: Oxidoreductase]]
[[Category: Joachimiak A]]
[[Category: Reductase]]
[[Category: Kim Y]]
[[Category: Structural genomic]]
[[Category: Zhou M]]
[[Category: Tunneling fold]]

Latest revision as of 08:14, 6 December 2023

Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0

3s19, resolution 1.50Å

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