Sulfatase-modifying factor: Difference between revisions
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== Function == | == Function == | ||
'''Sulfatase-modifying factor''' (SUMF) is an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing posttranslationally a cysteine residue in its substrate [[Sulfatase]] active site to 3-oxoalanine (C-α-formylglycine) residue<ref>PMID:17446859</ref>. | '''Sulfatase-modifying factor''' (SUMF) or '''formylglycine-generating enzyme''' is an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing posttranslationally a cysteine residue in its substrate [[Sulfatase]] active site to 3-oxoalanine (C-α-formylglycine) residue<ref>PMID:17446859</ref>. | ||
== Disease == | == Disease == | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[2aii]] - hSUMF-1 - human<br /> | [[2aii]], [[1y1e]], [[1y1g]], [[1y1f]], [[1y1j]], [[1y1i]], [[1z70]], [[1y1h]], [[5ssy]], [[5ssz]] - hSUMF-1 - human<br /> | ||
[[2aft]], [[2afy]], [[2hib]], [[2hi8]] - hSUMF-1 (mutant) <br /> | [[2aft]], [[2afy]], [[2hib]], [[2hi8]], [[5ssx]], [[8aru]] - hSUMF-1 (mutant) <br /> | ||
[[2aij]], [[2aik]] - hSUMF-1 (mutant) + peptide<br /> | [[2aij]], [[2aik]] - hSUMF-1 (mutant) + peptide<br /> | ||
[[1y4j]] - hSUMF-2 <br /> | [[1y4j]] - hSUMF-2 <br /> | ||
