2c40: Difference between revisions

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[[Image:2c40.gif|left|200px]]<br /><applet load="2c40" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2c40, resolution 2.20&Aring;" />
'''CRYSTAL STRUCTURE OF INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE FROM BACILLUS ANTHRACIS AT 2.2A RESOLUTION'''<br />


==About this Structure==
==CRYSTAL STRUCTURE OF INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE FROM BACILLUS ANTHRACIS AT 2.2A RESOLUTION==
2C40 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] with <scene name='pdbligand=RIB:'>RIB</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Purine_nucleosidase Purine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.1 3.2.2.1] Known structural/functional Site: <scene name='pdbsite=AC1:Rib+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C40 OCA].  
<StructureSection load='2c40' size='340' side='right'caption='[[2c40]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
[[Category: Bacillus anthracis]]
== Structural highlights ==
[[Category: Purine nucleosidase]]
<table><tr><td colspan='2'>[[2c40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C40 FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Blagova, E V.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=RIB:RIBOSE'>RIB</scene></td></tr>
[[Category: Brannigan, J A.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c40 OCA], [https://pdbe.org/2c40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c40 RCSB], [https://www.ebi.ac.uk/pdbsum/2c40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c40 ProSAT]</span></td></tr>
[[Category: Fogg, M J.]]
</table>
[[Category: Levdikov, V M.]]
== Function ==
[[Category: Moroz, O V.]]
[https://www.uniprot.org/uniprot/Q81QM4_BACAN Q81QM4_BACAN]
[[Category: Wilkinson, A J.]]
== Evolutionary Conservation ==
[[Category: Wilson, K S.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: CA]]
Check<jmol>
[[Category: RIB]]
  <jmolCheckbox>
[[Category: nucleoside hydrolase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/2c40_consurf.spt"</scriptWhenChecked>
[[Category: spine]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:44:37 2008''
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c40 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacillus anthracis str. Ames]]
[[Category: Large Structures]]
[[Category: Blagova EV]]
[[Category: Brannigan JA]]
[[Category: Fogg MJ]]
[[Category: Levdikov VM]]
[[Category: Moroz OV]]
[[Category: Wilkinson AJ]]
[[Category: Wilson KS]]