2c86: Difference between revisions

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==X-RAY STRUCTURE OF THE N AND C-TERMINAL DOMAIN OF CORONAVIRUS NUCLEOCAPSID PROTEIN.==
 
<StructureSection load='2c86' size='340' side='right' caption='[[2c86]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
==x-ray structure of the N and C-terminal domain of coronavirus nucleocapsid protein.==
<StructureSection load='2c86' size='340' side='right'caption='[[2c86]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2c86]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C86 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C86 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2c86]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C86 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2btl|2btl]], [[2bxx|2bxx]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c86 OCA], [http://pdbe.org/2c86 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c86 RCSB], [http://www.ebi.ac.uk/pdbsum/2c86 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c86 OCA], [https://pdbe.org/2c86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c86 RCSB], [https://www.ebi.ac.uk/pdbsum/2c86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c86 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NCAP_IBVBU NCAP_IBVBU] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.[HAMAP-Rule:MF_04097]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/2c86_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/2c86_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c86 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Avian infectious bronchitis virus]]
[[Category: Infectious bronchitis virus]]
[[Category: Bowman, B R]]
[[Category: Large Structures]]
[[Category: Collinson, E W]]
[[Category: Bowman BR]]
[[Category: Fan, H]]
[[Category: Collinson EW]]
[[Category: Jayaram, H]]
[[Category: Fan H]]
[[Category: Jayaram, J]]
[[Category: Jayaram H]]
[[Category: Lescar, J]]
[[Category: Jayaram J]]
[[Category: Ooi, A]]
[[Category: Lescar J]]
[[Category: Prasad, B V.V]]
[[Category: Ooi A]]
[[Category: Nucleocapsid protein]]
[[Category: Prasad BVV]]
[[Category: Phosphorylation]]
[[Category: Rna-binding]]
[[Category: Viral nucleoprotein]]