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[[Image:2c8g.jpg|left|200px]]


{{Structure
==Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (Free state, crystal form I)==
|PDB= 2c8g |SIZE=350|CAPTION= <scene name='initialview01'>2c8g</scene>, resolution 2.00&Aring;
<StructureSection load='2c8g' size='340' side='right'caption='[[2c8g]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+D'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[2c8g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C8G FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c8g OCA], [https://pdbe.org/2c8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c8g RCSB], [https://www.ebi.ac.uk/pdbsum/2c8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c8g ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c8g OCA], [http://www.ebi.ac.uk/pdbsum/2c8g PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2c8g RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/ARC3_CBDP ARC3_CBDP] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/2c8g_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c8g ConSurf].
<div style="clear:both"></div>


'''STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)'''
==See Also==
 
*[[Exoenzyme 3D structures|Exoenzyme 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2C8G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8G OCA].
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Boquet, P.]]
[[Category: Boquet P]]
[[Category: Flatau, G.]]
[[Category: Flatau G]]
[[Category: Menetrey, J.]]
[[Category: Menetrey J]]
[[Category: Menez, A.]]
[[Category: Menez A]]
[[Category: Stura, E A.]]
[[Category: Stura EA]]
[[Category: adp-ribosyltransferase]]
[[Category: artt motif]]
[[Category: bacterial toxin]]
[[Category: c3 exoenzyme]]
[[Category: glycosyltransferase]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:17:54 2008''

Latest revision as of 14:09, 13 December 2023

Structure of the PN loop Q182A mutant C3bot1 Exoenzyme (Free state, crystal form I)

2c8g, resolution 2.00Å

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