2iwq: Difference between revisions
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==7th PDZ domain of Multiple PDZ Domain Protein MPDZ== | ==7th PDZ domain of Multiple PDZ Domain Protein MPDZ== | ||
<StructureSection load='2iwq' size='340' side='right' caption='[[2iwq]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2iwq' size='340' side='right'caption='[[2iwq]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2iwq]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2iwq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IWQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IWQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iwq OCA], [https://pdbe.org/2iwq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iwq RCSB], [https://www.ebi.ac.uk/pdbsum/2iwq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iwq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MPDZ_HUMAN MPDZ_HUMAN] Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Berridge | [[Category: Arrowsmith C]] | ||
[[Category: Doyle | [[Category: Berridge G]] | ||
[[Category: Edwards | [[Category: Doyle DA]] | ||
[[Category: Elkins | [[Category: Edwards A]] | ||
[[Category: Papagrigoriou | [[Category: Elkins JM]] | ||
[[Category: Savitsky | [[Category: Papagrigoriou E]] | ||
[[Category: Smee | [[Category: Savitsky P]] | ||
[[Category: Sundstrom | [[Category: Smee CEA]] | ||
[[Category: Turnbull | [[Category: Sundstrom M]] | ||
[[Category: Ugochukwu | [[Category: Turnbull A]] | ||
[[Category: Weigelt | [[Category: Ugochukwu E]] | ||
[[Category: Weigelt J]] | |||
