2uzc: Difference between revisions
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<StructureSection load='2uzc' size='340' side='right'caption='[[2uzc]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='2uzc' size='340' side='right'caption='[[2uzc]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2uzc]] is a 5 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2uzc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UZC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uzc OCA], [https://pdbe.org/2uzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uzc RCSB], [https://www.ebi.ac.uk/pdbsum/2uzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uzc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PDLI5_HUMAN PDLI5_HUMAN] May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bunkoczi | [[Category: Bunkoczi G]] | ||
[[Category: Burgess-Brown | [[Category: Burgess-Brown N]] | ||
[[Category: Doyle D]] | |||
[[Category: Doyle | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Elkins J]] | ||
[[Category: Elkins | [[Category: Gileadi O]] | ||
[[Category: Gileadi | [[Category: Papagrigoriou E]] | ||
[[Category: Papagrigoriou | [[Category: Pike ACW]] | ||
[[Category: Pike | [[Category: Salah E]] | ||
[[Category: Salah | [[Category: Sundstrom M]] | ||
[[Category: Sundstrom | [[Category: Turnbull A]] | ||
[[Category: Turnbull | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Von Delft F]] | ||
[[Category: | |||
