2wei: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1== | ==Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1== | ||
<StructureSection load='2wei' size='340' side='right' caption='[[2wei]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='2wei' size='340' side='right'caption='[[2wei]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wei]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2wei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WEI FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VGG:1-TERT-BUTYL-3-(3-METHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>VGG</scene></td></tr> | |||
<tr><td class="sblockLbl"><b> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wei OCA], [https://pdbe.org/2wei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wei RCSB], [https://www.ebi.ac.uk/pdbsum/2wei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wei ProSAT]</span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </table> | ||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/A3FQ16_CRYPI A3FQ16_CRYPI] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/we/2wei_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/we/2wei_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wei ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 26: | Line 28: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2wei" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cryptosporidium parvum | [[Category: Cryptosporidium parvum Iowa II]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Artz | [[Category: Artz JD]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Chaikuad | [[Category: Chaikuad A]] | ||
[[Category: Doyle D]] | |||
[[Category: Doyle | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Fedorov O]] | ||
[[Category: Fedorov | [[Category: Finerty PJ]] | ||
[[Category: Finerty | [[Category: Heightman T]] | ||
[[Category: Heightman | [[Category: Hui R]] | ||
[[Category: Hui | [[Category: Indarte M]] | ||
[[Category: Indarte | [[Category: King O]] | ||
[[Category: King | [[Category: Kozieradzki I]] | ||
[[Category: Kozieradzki | [[Category: Lin L]] | ||
[[Category: Lin | [[Category: MacKenzie FI]] | ||
[[Category: | [[Category: Muniz J]] | ||
[[Category: Muniz | [[Category: Pike ACW]] | ||
[[Category: Pike | [[Category: Roos AK]] | ||
[[Category: Roos | [[Category: Schapira M]] | ||
[[Category: Schapira | [[Category: Shokat KM]] | ||
[[Category: Shokat | [[Category: Vedadi M]] | ||
[[Category: Vedadi | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Wernimont AK]] | ||
[[Category: Wernimont | [[Category: Zhang C]] | ||
[[Category: Zhang | [[Category: Von Delft F]] | ||
[[Category: | |||
