2wm8: Difference between revisions
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New page: '''Unreleased structure''' The entry 2wm8 is ON HOLD Authors: Yue, W.W., Shafqat, N., Pike, A.C.W., Chaikuad, A., Bray, J.E., Filippakopoulos, P., von Delft, F., Arrowsmith, C., Weigelt... |
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==Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)== | |||
<StructureSection load='2wm8' size='340' side='right'caption='[[2wm8]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2wm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WM8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wm8 OCA], [https://pdbe.org/2wm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wm8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MGDP1_HUMAN MGDP1_HUMAN] Magnesium-dependent phosphatase which may act as a tyrosine phosphatase. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/2wm8_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wm8 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith C]] | |||
[[Category: Bountra C]] | |||
[[Category: Bray JE]] | |||
[[Category: Burgess-Brown N]] | |||
[[Category: Chaikuad A]] | |||
[[Category: Edwards A]] | |||
[[Category: Filippakopoulos P]] | |||
[[Category: Hapka E]] | |||
[[Category: Oppermann U]] | |||
[[Category: Pike ACW]] | |||
[[Category: Pilka EW]] | |||
[[Category: Shafqat N]] | |||
[[Category: Weigelt J]] | |||
[[Category: Yue WW]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 16:02, 13 December 2023
Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)
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