2f87: Difference between revisions
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==Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus== | |||
<StructureSection load='2f87' size='340' side='right'caption='[[2f87]]' scene=''> | |||
== Structural highlights == | |||
| | <table><tr><td colspan='2'>[[2f87]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F87 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f87 OCA], [https://pdbe.org/2f87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f87 RCSB], [https://www.ebi.ac.uk/pdbsum/2f87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f87 ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
''' | == Publication Abstract from PubMed == | ||
== | |||
The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability. | The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability. | ||
Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus.,Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:16838833<ref>PMID:16838833</ref> | |||
Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 2f87" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Kanai A]] | |||
[[Category: Kawai G]] | |||
[[Category: Nakamura K]] | |||
[[Category: Okada K]] | |||
[[Category: Sakamoto T]] | |||
[[Category: Takahashi M]] | |||
