2wwe: Difference between revisions

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New page: '''Unreleased structure''' The entry 2wwe is ON HOLD Authors: ROOS, A.K., TRESAUGUES, L., ARROWSMITH, C.H., BERGLUND, H., BOUNTRA, C., COLLINS, R., EDWARDS, A.M., FLODIN, S., FLORES, A....
 
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'''Unreleased structure'''


The entry 2wwe is ON HOLD
==Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma==
<StructureSection load='2wwe' size='340' side='right'caption='[[2wwe]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2wwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwe OCA], [https://pdbe.org/2wwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwe RCSB], [https://www.ebi.ac.uk/pdbsum/2wwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P3C2G_HUMAN P3C2G_HUMAN] Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity). May play a role in SDF1A-stimulated chemotaxis (By similarity).[UniProtKB:O70167][UniProtKB:O70173]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2wwe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wwe ConSurf].
<div style="clear:both"></div>


Authors: ROOS, A.K., TRESAUGUES, L., ARROWSMITH, C.H., BERGLUND, H., BOUNTRA, C., COLLINS, R., EDWARDS, A.M., FLODIN, S., FLORES, A., GRASLUND, S., HAMMARSTROM, M., JOHANSSON, A., JOHANSSON, I., KALLAS, A., KARLBERG, T., KOTYENOVA, T., KOTZCH, A., KRAULIS, P., MARKOVA, N., MOCHE, M., NIELSEN, T.K., NYMAN, T., PERSSON, C., SCHULER, H., SCHUTZ, P., SIPONEN, M.I., SVENSSON, L., THORSELL, A.G., VAN DEN BERG, S., WAHLBERG, E., WEIGELT, J., WELIN, M., WISNIEWSKA, M., NORDLUND, P., STRUCTURAL GENOMICS CONSORTIU
==See Also==
 
*[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]]
Description: Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma
__TOC__
 
</StructureSection>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 12:45:59 2009''
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Berglund H]]
[[Category: Bountra C]]
[[Category: Collins R]]
[[Category: Edwards AM]]
[[Category: Flodin S]]
[[Category: Flores A]]
[[Category: Graslund S]]
[[Category: Hammarstrom M]]
[[Category: Johansson A]]
[[Category: Johansson I]]
[[Category: Kallas A]]
[[Category: Karlberg T]]
[[Category: Kotyenova T]]
[[Category: Kotzch A]]
[[Category: Kraulis P]]
[[Category: Markova N]]
[[Category: Moche M]]
[[Category: Nielsen TK]]
[[Category: Nordlund P]]
[[Category: Nyman T]]
[[Category: Persson C]]
[[Category: Roos AK]]
[[Category: Schuler H]]
[[Category: Schutz P]]
[[Category: Siponen MI]]
[[Category: Svensson L]]
[[Category: Thorsell AG]]
[[Category: Tresaugues L]]
[[Category: Van Der Berg S]]
[[Category: Wahlberg E]]
[[Category: Weigelt J]]
[[Category: Welin M]]
[[Category: Wisniewska M]]
Retrieved from "https://proteopedia.org/2wwe"