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==Crystal structure of E. coli FabI in complex with NADH and CG400549==
==Crystal structure of E. coli FabI in complex with NADH and CG400549==
<StructureSection load='4cv2' size='340' side='right' caption='[[4cv2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4cv2' size='340' side='right'caption='[[4cv2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cv2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CV2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CV2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cv2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CV2 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=PT6:1-(3-AMINO-2-METHYLBENZYL)-4-[2-(THIOPHEN-2-YL)ETHOXY]PYRIDIN-2(1H)-ONE'>PT6</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cuz|4cuz]], [[4cv0|4cv0]], [[4cv1|4cv1]], [[4cv3|4cv3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=PT6:1-(3-AMINO-2-METHYLBENZYL)-4-[2-(THIOPHEN-2-YL)ETHOXY]PYRIDIN-2(1H)-ONE'>PT6</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cv2 OCA], [https://pdbe.org/4cv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cv2 RCSB], [https://www.ebi.ac.uk/pdbsum/4cv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cv2 ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cv2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cv2 RCSB], [http://www.ebi.ac.uk/pdbsum/4cv2 PDBsum]</span></td></tr>
</table>
<table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4cv2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecobd]]
[[Category: Large Structures]]
[[Category: Chang, A.]]
[[Category: Chang A]]
[[Category: Kisker, C.]]
[[Category: Kisker C]]
[[Category: Schiebel, J.]]
[[Category: Schiebel J]]
[[Category: Shah, S.]]
[[Category: Shah S]]
[[Category: Tareilus, M.]]
[[Category: Tareilus M]]
[[Category: Tonge, P J.]]
[[Category: Tonge PJ]]
[[Category: Ecfabi]]
[[Category: Fatty acid biosynthesis]]
[[Category: Lipid synthesis]]
[[Category: Oxidoreductase]]
[[Category: Short-chain dehydrogenase/reductase superfamily]]