1ix1: Difference between revisions

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{{Seed}}
[[Image:1ix1.png|left|200px]]


<!--
==Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin==
The line below this paragraph, containing "STRUCTURE_1ix1", creates the "Structure Box" on the page.
<StructureSection load='1ix1' size='340' side='right'caption='[[1ix1]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ix1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IX1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=MHA:(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC+ACID'>MHA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1ix1|  PDB=1ix1  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ix1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ix1 OCA], [https://pdbe.org/1ix1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ix1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ix1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ix1 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin===
== Function ==
 
[https://www.uniprot.org/uniprot/DEF_PSEAE DEF_PSEAE] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1IX1 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IX1 OCA].  
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ix1_consurf.spt"</scriptWhenChecked>
<ref group="xtra">PMID:15382235</ref><references group="xtra"/>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Peptide deformylase]]
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ix1 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Ahn, H J.]]
[[Category: Ahn HJ]]
[[Category: Han, B W.]]
[[Category: Han BW]]
[[Category: Kim, H W.]]
[[Category: Kim H-W]]
[[Category: Lee, B I.]]
[[Category: Lee BI]]
[[Category: Lee, H H.]]
[[Category: Lee HH]]
[[Category: Lee, J Y.]]
[[Category: Lee JY]]
[[Category: Suh, S W.]]
[[Category: Suh SW]]
[[Category: Yang, J K.]]
[[Category: Yang JK]]
[[Category: Yoon, H J.]]
[[Category: Yoon H-J]]
[[Category: Protein-inhibitor complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:53:19 2009''
Retrieved from "https://proteopedia.org/1ix1"