2ogj: Difference between revisions

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[[Image:2ogj.gif|left|200px]]


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==Crystal structure of a dihydroorotase==
The line below this paragraph, containing "STRUCTURE_2ogj", creates the "Structure Box" on the page.
<StructureSection load='2ogj' size='340' side='right'caption='[[2ogj]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ogj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabrum_str._C58 Agrobacterium fabrum str. C58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2ogj| PDB=2ogj |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogj OCA], [https://pdbe.org/2ogj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogj RCSB], [https://www.ebi.ac.uk/pdbsum/2ogj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogj ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ogj TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEACT_AGRFC DEACT_AGRFC] Esterase that catalyzes the deacetylation of acetyl-(R)-mandelate (in vitro). Can also hydrolyze acetyl glycolate, but with lower efficiency. Has very low N-acetyl-D-amino acid deacetylase activity with N-acetyl-D-serine and N-acetyl-D-threonine (in vitro). Theoretical substrate docking studies suggest that other N-acetylated amino acids may optimally occupy the active site and may in fact be the physiological substrates.<ref>PMID:23214420</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ogj ConSurf].
<div style="clear:both"></div>


'''Crystal structure of a dihydroorotase'''
==See Also==
 
*[[Dihydroorotase 3D structures|Dihydroorotase 3D structures]]
 
== References ==
==About this Structure==
<references/>
2OGJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGJ OCA].
__TOC__
[[Category: Agrobacterium tumefaciens]]
</StructureSection>
[[Category: Single protein]]
[[Category: Agrobacterium fabrum str. C58]]
[[Category: Burley, S K.]]
[[Category: Large Structures]]
[[Category: Kumaran, D.]]
[[Category: Burley SK]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Kumaran D]]
[[Category: Sugadev, R.]]
[[Category: Sugadev R]]
[[Category: Swaminathan, S.]]
[[Category: Swaminathan S]]
[[Category: 9244b]]
[[Category: Amido hydrolase]]
[[Category: Binuclear zinc]]
[[Category: Imidazole complex]]
[[Category: New york structural genomix research consortium]]
[[Category: Nysgxrc]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Tim barrel]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 10:52:03 2008''
Retrieved from "https://proteopedia.org/2ogj"