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==The crystal structure of the phosphoenolpyruvate synthase from Neisseria meningitidis==
==The crystal structure of the phosphoenolpyruvate synthase from Neisseria meningitidis==
<StructureSection load='2ols' size='340' side='right' caption='[[2ols]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2ols' size='340' side='right'caption='[[2ols]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ols]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OLS FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ols]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OLS FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ppsA, NMB0618 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate,_water_dikinase Pyruvate, water dikinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.9.2 2.7.9.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ols FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ols OCA], [https://pdbe.org/2ols PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ols RCSB], [https://www.ebi.ac.uk/pdbsum/2ols PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ols ProSAT], [https://www.topsan.org/Proteins/MCSG/2ols TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ols FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ols OCA], [http://pdbe.org/2ols PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ols RCSB], [http://www.ebi.ac.uk/pdbsum/2ols PDBsum], [http://www.topsan.org/Proteins/MCSG/2ols TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PPSA_NEIMB PPSA_NEIMB]] Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.  
[https://www.uniprot.org/uniprot/PPSA_NEIMB PPSA_NEIMB] Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/2ols_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/2ols_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ols ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Neimb]]
[[Category: Large Structures]]
[[Category: Pyruvate, water dikinase]]
[[Category: Neisseria meningitidis MC58]]
[[Category: Bargassa, M]]
[[Category: Bargassa M]]
[[Category: Duggan, E]]
[[Category: Duggan E]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Structural genomic]]
[[Category: Zhang R]]
[[Category: Zhang, R]]
[[Category: Mcsg]]
[[Category: Neisseria meningitidi]]
[[Category: PSI, Protein structure initiative]]
[[Category: The phosphoenolpyruvate synthase]]
[[Category: Transferase]]

Latest revision as of 00:20, 28 December 2023

The crystal structure of the phosphoenolpyruvate synthase from Neisseria meningitidis

2ols, resolution 2.40Å

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