4oxf: Difference between revisions
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New page: '''Unreleased structure''' The entry 4oxf is ON HOLD Authors: Blanco, J. A., Boix, E., Moussaoui, M., Salazar, V. A. Description: Structure of ECP in complex with citrate ions at 1.50 ... |
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==Structure of ECP in complex with citrate ions at 1.50 Angstroms== | |||
<StructureSection load='4oxf' size='340' side='right'caption='[[4oxf]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4oxf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OXF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oxf OCA], [https://pdbe.org/4oxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oxf RCSB], [https://www.ebi.ac.uk/pdbsum/4oxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oxf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ECP_HUMAN ECP_HUMAN] Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.<ref>PMID:2501794</ref> <ref>PMID:19450231</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Blanco JA]] | |||
[[Category: Boix E]] | |||
[[Category: Moussaoui M]] | |||
[[Category: Salazar VA]] | |||
