4unl: Difference between revisions

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~~'''Unreleased structure'''~~

~~The~~ entry ~~4unl~~ is ~~ON HOLD until Paper Publication~~

==Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human==

== Structural highlights ==

<table><tr><td colspan='2'>[[4unl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UNL FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4unl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unl OCA], [https://pdbe.org/4unl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4unl RCSB], [https://www.ebi.ac.uk/pdbsum/4unl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4unl ProSAT]</span></td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[https://omim.org/entry/190450 190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.

== Function ==

[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]

~~Authors~~: DeLaMora-DeLaMora, I~~., Torres-Larios, A.,~~ Enriquez-Flores, S~~., Mendez, S.T., Castillo~~-~~Villanueva, A.,~~ Gomez-Manzo, S., Lopez-Velazquez, G., Marcial-Quino, J~~., Torres~~-~~Arroyo, A., Garcia-Torres, I.,~~ Reyes-Vivas, H~~., Oria~~-~~Hernandez, J.~~

==See Also==

*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]

~~Description~~: ~~Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human~~

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Castillo-Villanueva A]]

[[Category: DeLaMora-DeLaMora I]]

[[Category: Enriquez-Flores S]]

[[Category: Garcia-Torres I]]

[[Category: Gomez-Manzo S]]

[[Category: Lopez-Velazquez G]]

[[Category: Marcial-Quino J]]

[[Category: Mendez ST]]

[[Category: Oria-Hernandez J]]

[[Category: Reyes-Vivas H]]

[[Category: Torres-Arroyo A]]

[[Category: Torres-Larios A]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4unl is ON HOLD  until Paper Publication
+==Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human==
+<StructureSection load='4unl' size='340' side='right'caption='[[4unl]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4unl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UNL FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4unl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unl OCA], [https://pdbe.org/4unl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4unl RCSB], [https://www.ebi.ac.uk/pdbsum/4unl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4unl ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[https://omim.org/entry/190450 190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
+== Function ==
+[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]
-Authors: DeLaMora-DeLaMora, I., Torres-Larios, A., Enriquez-Flores, S., Mendez, S.T., Castillo-Villanueva, A., Gomez-Manzo, S., Lopez-Velazquez, G., Marcial-Quino, J., Torres-Arroyo, A., Garcia-Torres, I., Reyes-Vivas, H., Oria-Hernandez, J.
+==See Also==
+*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
-Description: Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Castillo-Villanueva A]]
+[[Category: DeLaMora-DeLaMora I]]
+[[Category: Enriquez-Flores S]]
+[[Category: Garcia-Torres I]]
+[[Category: Gomez-Manzo S]]
+[[Category: Lopez-Velazquez G]]
+[[Category: Marcial-Quino J]]
+[[Category: Mendez ST]]
+[[Category: Oria-Hernandez J]]
+[[Category: Reyes-Vivas H]]
+[[Category: Torres-Arroyo A]]
+[[Category: Torres-Larios A]]