4v5i: Difference between revisions

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==STRUCTURE OF THE PHAGE P2 BASEPLATE IN ITS ACTIVATED CONFORMATION WITH CA==
 
<StructureSection load='4v5i' size='340' side='right' caption='[[4v5i]], [[Resolution|resolution]] 5.46&Aring;' scene=''>
==Structure of the Phage P2 Baseplate in its Activated Conformation with Ca==
<StructureSection load='4v5i' size='340' side='right'caption='[[4v5i]], [[Resolution|resolution]] 5.46&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4v5i]] is a 54 chain structure. This structure supersedes and combines the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x54 2x54] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x5a 2x5a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V5I FirstGlance]. <br>
<table><tr><td colspan='2'>[[4v5i]] is a 54 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_virus_P2 Lactococcus virus P2]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x54 2x54] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x5a 2x5a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V5I FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5.464&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2x53|2x53]], [[2wzp|2wzp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v5i RCSB], [http://www.ebi.ac.uk/pdbsum/4v5i PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v5i OCA], [https://pdbe.org/4v5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v5i RCSB], [https://www.ebi.ac.uk/pdbsum/4v5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v5i ProSAT]</span></td></tr>
</table>
</table>
{{Large structure}}
== Function ==
[https://www.uniprot.org/uniprot/RBP_BPLP2 RBP_BPLP2] Binds to the host phosphopolysaccharides at the onset of infection. Upon activation by calcium, the receptor binding proteins change their conformation, presenting their binding sites to the host, and a channel opens at the bottom of the baseplate for DNA ejection.<ref>PMID:20351260</ref> <ref>PMID:24027307</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4v5i" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bebeacua, C]]
[[Category: Lactococcus virus P2]]
[[Category: Bron, P]]
[[Category: Large Structures]]
[[Category: Cambillau, C]]
[[Category: Bebeacua C]]
[[Category: Campanacci, V]]
[[Category: Bron P]]
[[Category: Lichiere, J]]
[[Category: Cambillau C]]
[[Category: Moineau, S]]
[[Category: Campanacci V]]
[[Category: Ortiz-Lombardia, M]]
[[Category: Lichiere J]]
[[Category: Sciara, G]]
[[Category: Moineau S]]
[[Category: Tremblay, D]]
[[Category: Ortiz-Lombardia M]]
[[Category: VanHeel, M]]
[[Category: Sciara G]]
[[Category: Lactococcus lacti]]
[[Category: Tremblay D]]
[[Category: Siphoviridae]]
[[Category: Van Heel M]]
[[Category: Viral protein]]
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