7b1u: Difference between revisions

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'''Unreleased structure'''


The entry 7b1u is ON HOLD  until Paper Publication
==Crystal structure of a shortened IpgC variant in complex with 3-(3,4-difluorophenyl)-1H,4H,6H,7H-imidazo[2,1-c][1,2,4]triazine==
 
<StructureSection load='7b1u' size='340' side='right'caption='[[7b1u]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
Authors: Gardonyi, M., Heine, A., Klebe, G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7b1u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B1U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B1U FirstGlance]. <br>
Description: Crystal structure of a shortened IpgC variant in complex with 3-(3,4-difluorophenyl)-1H,4H,6H,7H-imidazo[2,1-c][1,2,4]triazine
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=L2K:3-[3,4-bis(fluoranyl)phenyl]-1,4,6,7-tetrahydroimidazo[2,1-c][1,2,4]triazine'>L2K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
[[Category: Gardonyi, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b1u OCA], [https://pdbe.org/7b1u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b1u RCSB], [https://www.ebi.ac.uk/pdbsum/7b1u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b1u ProSAT]</span></td></tr>
[[Category: Klebe, G]]
</table>
[[Category: Heine, A]]
== Function ==
[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Shigella flexneri]]
[[Category: Gardonyi M]]
[[Category: Heine A]]
[[Category: Klebe G]]
Retrieved from "https://proteopedia.org/7b1u"