7b9w: Difference between revisions
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New page: '''Unreleased structure''' The entry 7b9w is ON HOLD Authors: Koekemoer, L., Steindel, M., Fairhead, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Krojer, T., Structu... |
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==Crystal structure of MurE from E.coli in complex with Z757284380== | |||
<StructureSection load='7b9w' size='340' side='right'caption='[[7b9w]], [[Resolution|resolution]] 1.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7b9w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B9W FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=T4H:3-Chloro-N-[2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethyl]benzamide'>T4H</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b9w OCA], [https://pdbe.org/7b9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b9w RCSB], [https://www.ebi.ac.uk/pdbsum/7b9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b9w ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MURE_ECOLI MURE_ECOLI] Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine.<ref>PMID:2269304</ref> <ref>PMID:3905407</ref> <ref>PMID:11124264</ref> | |||
==See Also== | |||
*[[Mur ligase|Mur ligase]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Bountra | [[Category: Escherichia coli K-12]] | ||
[[Category: Edwards | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: Edwards AM]] | ||
[[Category: | [[Category: Fairhead M]] | ||
[[Category: | [[Category: Koekemoer L]] | ||
[[Category: Krojer T]] | |||
[[Category: Steindel M]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 12:24, 1 February 2024
Crystal structure of MurE from E.coli in complex with Z757284380
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