7ngi: Difference between revisions
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New page: '''Unreleased structure''' The entry 7ngi is ON HOLD until Paper Publication Authors: Tomlinson, C.W.E., Tatum, N.J., Pohl, E. Description: Mycobacterium tuberculosis transcriptional r... |
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==Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound== | |||
<StructureSection load='7ngi' size='340' side='right'caption='[[7ngi]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7ngi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NGI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U9T:~{N}-[2-(2-fluorophenyl)ethyl]-4-methyl-piperidine-1-carboxamide'>U9T</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ngi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ngi OCA], [https://pdbe.org/7ngi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ngi RCSB], [https://www.ebi.ac.uk/pdbsum/7ngi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ngi ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | |||
==See Also== | |||
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Pohl | __TOC__ | ||
[[Category: Tatum | </StructureSection> | ||
[[Category: Tomlinson | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Pohl E]] | |||
[[Category: Tatum NJ]] | |||
[[Category: Tomlinson CWE]] | |||
Latest revision as of 12:34, 1 February 2024
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
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