1cuk: Difference between revisions

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{{Seed}}
[[Image:1cuk.png|left|200px]]


<!--
==ESCHERICHIA COLI RUVA PROTEIN AT PH 4.9 AND ROOM TEMPERATURE==
The line below this paragraph, containing "STRUCTURE_1cuk", creates the "Structure Box" on the page.
<StructureSection load='1cuk' size='340' side='right'caption='[[1cuk]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1cuk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CUK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cuk OCA], [https://pdbe.org/1cuk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cuk RCSB], [https://www.ebi.ac.uk/pdbsum/1cuk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cuk ProSAT]</span></td></tr>
{{STRUCTURE_1cuk| PDB=1cuk |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RUVA_ECOLI RUVA_ECOLI] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.<ref>PMID:8433990</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/1cuk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cuk ConSurf].
<div style="clear:both"></div>


===ESCHERICHIA COLI RUVA PROTEIN AT PH 4.9 AND ROOM TEMPERATURE===
==See Also==
 
*[[Helicase 3D structures|Helicase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_8832889}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 8832889 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_8832889}}
 
==About this Structure==
1CUK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CUK OCA].
 
==Reference==
Crystal structure of DNA recombination protein RuvA and a model for its binding to the Holliday junction., Rafferty JB, Sedelnikova SE, Hargreaves D, Artymiuk PJ, Baker PJ, Sharples GJ, Mahdi AA, Lloyd RG, Rice DW, Science. 1996 Oct 18;274(5286):415-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8832889 8832889]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Rafferty, J B.]]
[[Category: Rafferty JB]]
[[Category: Rice, D W.]]
[[Category: Rice DW]]
[[Category: Dna recombination]]
[[Category: Dna repair]]
[[Category: Dna-binding]]
[[Category: Helicase]]
[[Category: Sos response]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:23:31 2008''
Retrieved from "https://proteopedia.org/1cuk"