1d3a: Difference between revisions

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{{Seed}}
[[Image:1d3a.png|left|200px]]


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==CRYSTAL STRUCTURE OF THE WILD TYPE HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM==
The line below this paragraph, containing "STRUCTURE_1d3a", creates the "Structure Box" on the page.
<StructureSection load='1d3a' size='340' side='right'caption='[[1d3a]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1d3a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D3A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_1d3a|  PDB=1d3a |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d3a OCA], [https://pdbe.org/1d3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d3a RCSB], [https://www.ebi.ac.uk/pdbsum/1d3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d3a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDH_HALMA MDH_HALMA] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/1d3a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d3a ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF THE WILD TYPE HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM===
==See Also==
 
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_10653643}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 10653643 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10653643}}
 
==About this Structure==
1D3A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D3A OCA].
 
==Reference==
Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 A resolution structures of the wild type and a mutant of malate dehydrogenase from Haloarcula marismortui., Richard SB, Madern D, Garcin E, Zaccai G, Biochemistry. 2000 Feb 8;39(5):992-1000. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10653643 10653643]
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
[[Category: Malate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Garcin E]]
[[Category: Garcin, E.]]
[[Category: Madern D]]
[[Category: Madern, D.]]
[[Category: Richard SB]]
[[Category: Richard, S B.]]
[[Category: Zaccai G]]
[[Category: Zaccai, G.]]
[[Category: Rossmann fold and 3 sorts of complex salt bridge]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:16:58 2008''

Latest revision as of 06:48, 7 February 2024

CRYSTAL STRUCTURE OF THE WILD TYPE HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM

1d3a, resolution 2.94Å

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