1d3y: Difference between revisions

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[[Image:1d3y.png|left|200px]]


{{STRUCTURE_1d3y|  PDB=1d3y  |  SCENE=  }}
==STRUCTURE OF THE DNA TOPOISOMERASE VI A SUBUNIT==
 
<StructureSection load='1d3y' size='340' side='right'caption='[[1d3y]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===STRUCTURE OF THE DNA TOPOISOMERASE VI A SUBUNIT===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1d3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D3Y FirstGlance]. <br>
{{ABSTRACT_PUBMED_10545127}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d3y OCA], [https://pdbe.org/1d3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d3y RCSB], [https://www.ebi.ac.uk/pdbsum/1d3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d3y ProSAT]</span></td></tr>
[[1d3y]] is a 2 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D3Y OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/TOP6A_METJA TOP6A_METJA] Relaxes both positive and negative superturns and exhibits a strong decatenase activity.<ref>PMID:10545127</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/1d3y_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d3y ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Topoisomerase|Topoisomerase]]
*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:010545127</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Berger, J M.]]
[[Category: Berger JM]]
[[Category: DeAngelis, K A.]]
[[Category: DeAngelis KA]]
[[Category: Keck, J L.]]
[[Category: Keck JL]]
[[Category: Nichols, M D.]]
[[Category: Nichols MD]]
[[Category: Dna binding protein]]
[[Category: Isomerase]]
[[Category: Spo11 homolog]]
[[Category: Topoisomerase vi]]
Retrieved from "https://proteopedia.org/1d3y"