1ds7: Difference between revisions

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{{Seed}}
[[Image:1ds7.png|left|200px]]


<!--
==A MINOR FMN-DEPENDENT NITROREDUCTASE FROM ESCHERICHIA COLI B==
The line below this paragraph, containing "STRUCTURE_1ds7", creates the "Structure Box" on the page.
<StructureSection load='1ds7' size='340' side='right'caption='[[1ds7]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ds7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_B Escherichia coli B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DS7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
{{STRUCTURE_1ds7| PDB=1ds7 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ds7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ds7 OCA], [https://pdbe.org/1ds7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ds7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ds7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ds7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NFSB_ECOLI NFSB_ECOLI] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.<ref>PMID:15684426</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/1ds7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ds7 ConSurf].
<div style="clear:both"></div>


===A MINOR FMN-DEPENDENT NITROREDUCTASE FROM ESCHERICHIA COLI B===
==See Also==
 
*[[Nitroreductase 3D structures|Nitroreductase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_11020276}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 11020276 is the PubMed ID number.
</StructureSection>
-->
[[Category: Escherichia coli B]]
{{ABSTRACT_PUBMED_11020276}}
[[Category: Large Structures]]
 
[[Category: Neidle S]]
==About this Structure==
[[Category: Parkinson G]]
1DS7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS7 OCA].
[[Category: Skelly J]]
 
==Reference==
<ref group="xtra">PMID:11020276</ref><references group="xtra"/>
[[Category: 6,7-dihydropteridine reductase]]
[[Category: Escherichia coli]]
[[Category: Neidle, S.]]
[[Category: Parkinson, G.]]
[[Category: Skelly, J.]]
[[Category: Flavoprotein]]
[[Category: Fmn]]
[[Category: Nitroreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:25:18 2009''
Retrieved from "https://proteopedia.org/1ds7"