1emv: Difference between revisions

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{{Seed}}
[[Image:1emv.png|left|200px]]


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==CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS)==
The line below this paragraph, containing "STRUCTURE_1emv", creates the "Structure Box" on the page.
<StructureSection load='1emv' size='340' side='right'caption='[[1emv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1emv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EMV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_1emv| PDB=1emv |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1emv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1emv OCA], [https://pdbe.org/1emv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1emv RCSB], [https://www.ebi.ac.uk/pdbsum/1emv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1emv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IMM9_ECOLX IMM9_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/em/1emv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1emv ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS)===
==See Also==
 
*[[Colicin 3D structures|Colicin 3D structures]]
 
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
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{{ABSTRACT_PUBMED_10966813}}
 
==About this Structure==
1EMV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EMV OCA].
 
==Reference==
Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes., Kuhlmann UC, Pommer AJ, Moore GR, James R, Kleanthous C, J Mol Biol. 2000 Sep 1;301(5):1163-78. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10966813 10966813]
[[Category: Deoxyribonuclease I]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: James, R.]]
[[Category: James R]]
[[Category: Kleanthous, C.]]
[[Category: Kleanthous C]]
[[Category: Kuhlmann, U C.]]
[[Category: Kuhlmann UC]]
[[Category: Moore, G M.]]
[[Category: Moore GM]]
[[Category: Pommer, A J.]]
[[Category: Pommer AJ]]
[[Category: Protein-protein complex]]
 
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Retrieved from "https://proteopedia.org/1emv"