1ezf: Difference between revisions

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{{Seed}}
[[Image:1ezf.png|left|200px]]


<!--
==CRYSTAL STRUCTURE OF HUMAN SQUALENE SYNTHASE==
The line below this paragraph, containing "STRUCTURE_1ezf", creates the "Structure Box" on the page.
<StructureSection load='1ezf' size='340' side='right'caption='[[1ezf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ezf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EZF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IN0:N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL)+-5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E]+[1,4]OXAZEPIN-3-YL]-ACETYL}-ASPARTIC+ACID'>IN0</scene></td></tr>
{{STRUCTURE_1ezf| PDB=1ezf |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ezf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezf OCA], [https://pdbe.org/1ezf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ezf RCSB], [https://www.ebi.ac.uk/pdbsum/1ezf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FDFT_HUMAN FDFT_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/1ezf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ezf ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF HUMAN SQUALENE SYNTHASE===
==See Also==
 
*[[Squalene synthase|Squalene synthase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_10896663}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 10896663 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_10896663}}
 
==About this Structure==
1EZF is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZF OCA].
 
==Reference==
<ref group="xtra">PMID:10896663</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Squalene synthase]]
[[Category: Large Structures]]
[[Category: Danley, D E.]]
[[Category: Danley DE]]
[[Category: Hamanaka, E S.]]
[[Category: Hamanaka ES]]
[[Category: Harwood, H J.]]
[[Category: Harwood HJ]]
[[Category: Hayward, C M.]]
[[Category: Hayward CM]]
[[Category: Mazzalupo, S M.]]
[[Category: Mazzalupo SM]]
[[Category: Pandit, J.]]
[[Category: Pandit J]]
[[Category: Pauly, T A.]]
[[Category: Pauly TA]]
[[Category: Schulte, G K.]]
[[Category: Schulte GK]]
[[Category: Thompson, J F.]]
[[Category: Thompson JF]]
[[Category: All alpha-helix]]
[[Category: Isoprenoid synthase fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:39:02 2009''
Retrieved from "https://proteopedia.org/1ezf"