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[[Image:1fbw.png|left|200px]]


{{STRUCTURE_1fbw|  PDB=1fbw  |  SCENE=  }}
==Crystal structure of the cellulase CEL48F from C. cellulolyticum in complex with cellohexaose==
 
<StructureSection load='1fbw' size='340' side='right'caption='[[1fbw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===Crystal structure of the cellulase CEL48F from C. cellulolyticum in complex with cellohexaose===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1fbw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruminiclostridium_cellulolyticum Ruminiclostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FBW FirstGlance]. <br>
{{ABSTRACT_PUBMED_10985769}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900009:alpha-maltotriose'>PRD_900009</scene>, <scene name='pdbligand=PRD_900035:alpha-maltohexaose'>PRD_900035</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fbw OCA], [https://pdbe.org/1fbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fbw RCSB], [https://www.ebi.ac.uk/pdbsum/1fbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fbw ProSAT]</span></td></tr>
[[1fbw]] is a 1 chain structure of [[Glucanase]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FBW OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/GUNF_RUMCH GUNF_RUMCH] Probable endoglucanase involved in the degradation of cellulose or related beta-glucans.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/1fbw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fbw ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glucanase|Glucanase]]
*[[Glucanase 3D structures|Glucanase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010985769</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Cellulase]]
[[Category: Ruminiclostridium cellulolyticum]]
[[Category: Clostridium cellulolyticum]]
[[Category: Belaich JP]]
[[Category: Belaich, J P.]]
[[Category: Driguez H]]
[[Category: Driguez, H.]]
[[Category: Haser R]]
[[Category: Haser, R.]]
[[Category: Parsiegla G]]
[[Category: Parsiegla, G.]]
[[Category: Reverbel-Leroy C]]
[[Category: Reverbel-Leroy, C.]]
[[Category: Tardif C]]
[[Category: Tardif, C.]]
[[Category: Cellulase]]
[[Category: Hydrolase]]
[[Category: Protein-cellohexaose complex]]

Latest revision as of 07:13, 7 February 2024

Crystal structure of the cellulase CEL48F from C. cellulolyticum in complex with cellohexaose

1fbw, resolution 2.00Å

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