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| | ==CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER== |
| The line below this paragraph, containing "STRUCTURE_1fe6", creates the "Structure Box" on the page.
| | <StructureSection load='1fe6' size='340' side='right'caption='[[1fe6]], [[Resolution|resolution]] 1.80Å' scene=''> |
| You may change the PDB parameter (which sets the PDB file loaded into the applet)
| | == Structural highlights == |
| or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
| | <table><tr><td colspan='2'>[[1fe6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylothermus_marinus Staphylothermus marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FE6 FirstGlance]. <br> |
| or leave the SCENE parameter empty for the default display.
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
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| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fe6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fe6 OCA], [https://pdbe.org/1fe6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fe6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fe6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fe6 ProSAT]</span></td></tr> |
| {{STRUCTURE_1fe6| PDB=1fe6 | SCENE= }}
| | </table> |
| | | == Function == |
| '''CRYSTAL STRUCTURE OF A NATURALLY OCCURING PARALLEL RIGHT-HANDED COILED-COIL TETRAMER'''
| | [https://www.uniprot.org/uniprot/Q54436_STAMA Q54436_STAMA] |
| | | __TOC__ |
| | | </StructureSection> |
| ==Overview== | | [[Category: Large Structures]] |
| The crystal structure of a polypeptide chain fragment from the surface layer protein tetrabrachion from Staphylothermus marinus has been determined at 1.8 A resolution. As proposed on the basis of the presence of 11-residue repeats, the polypeptide chain fragment forms a parallel right-handed coiled coil structure. Complementary hydrophobic interactions and complex networks of surface salt bridges result in an extremely thermostable tetrameric structure with remarkable properties. In marked contrast to left-handed coiled coil tetramers, the right-handed coiled coil reveals large hydrophobic cavities that are filled with water molecules. As a consequence, the packing of the hydrophobic core differs markedly from that of a right-handed parallel coiled coil tetramer that was designed on the basis of left-handed coiled coil structures.
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| ==About this Structure== | |
| 1FE6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylothermus_marinus Staphylothermus marinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FE6 OCA].
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| ==Reference== | |
| Crystal structure of a naturally occurring parallel right-handed coiled coil tetramer., Stetefeld J, Jenny M, Schulthess T, Landwehr R, Engel J, Kammerer RA, Nat Struct Biol. 2000 Sep;7(9):772-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10966648 10966648]
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| [[Category: Single protein]] | |
| [[Category: Staphylothermus marinus]] | | [[Category: Staphylothermus marinus]] |
| [[Category: Stetefeld, J.]] | | [[Category: Stetefeld J]] |
| [[Category: Right handed coiled coil]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:13:30 2008''
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