1i5e: Difference between revisions

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{{Seed}}
[[Image:1i5e.png|left|200px]]


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==CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP==
The line below this paragraph, containing "STRUCTURE_1i5e", creates the "Structure Box" on the page.
<StructureSection load='1i5e' size='340' side='right'caption='[[1i5e]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1i5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I5E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
{{STRUCTURE_1i5e| PDB=1i5e |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i5e OCA], [https://pdbe.org/1i5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i5e RCSB], [https://www.ebi.ac.uk/pdbsum/1i5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i5e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UPP_BACCL UPP_BACCL] Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<ref>PMID:12037295</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/1i5e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i5e ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP===
==See Also==
 
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_12037295}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 12037295 is the PubMed ID number.
</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_12037295}}
[[Category: Kadziola A]]
 
[[Category: Larsen S]]
==About this Structure==
[[Category: Neuhard J]]
1I5E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I5E OCA].
 
==Reference==
Structure of product-bound Bacillus caldolyticus uracil phosphoribosyltransferase confirms ordered sequential substrate binding., Kadziola A, Neuhard J, Larsen S, Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):936-45. Epub, 2002 May 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12037295 12037295]
[[Category: Bacillus caldolyticus]]
[[Category: Single protein]]
[[Category: Uracil phosphoribosyltransferase]]
[[Category: Kadziola, A.]]
[[Category: Larsen, S.]]
[[Category: Neuhard, J.]]
[[Category: Bacillus caldolyticus]]
[[Category: Salvage pathway]]
[[Category: Uracil phosphoribosyltransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 10:26:47 2008''
Retrieved from "https://proteopedia.org/1i5e"