1juc: Difference between revisions

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[[Image:1juc.gif|left|200px]]


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==Crystal Structure Analysis of a Holliday Junction Formed by CCGGTACCGG==
The line below this paragraph, containing "STRUCTURE_1juc", creates the "Structure Box" on the page.
<StructureSection load='1juc' size='340' side='right'caption='[[1juc]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1juc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JUC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1juc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1juc OCA], [https://pdbe.org/1juc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1juc RCSB], [https://www.ebi.ac.uk/pdbsum/1juc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1juc ProSAT]</span></td></tr>
{{STRUCTURE_1juc|  PDB=1juc  |  SCENE= }}
</table>
 
__TOC__
'''Crystal Structure Analysis of a Holliday Junction Formed by CCGGTACCGG'''
</StructureSection>
 
[[Category: Large Structures]]
 
[[Category: Cardin CJ]]
==Overview==
[[Category: Gale BC]]
DNA-strand exchange is a vital step in the recombination process, of which a key intermediate is the four-way DNA Holliday junction formed transiently in most living organisms. Here, the single-crystal structure at a resolution of 2.35 A of such a DNA junction formed by d(CCGGTACCGG)(2), which has crystallized in a more highly symmetrical packing mode to that previously observed for the same sequence, is presented. In this case, the structure is isomorphous to the mismatch sequence d(CCGGGACCGG)(2), which reveals the roles of both lattice and DNA sequence in determining the junction geometry. The helices cross at the larger angle of 43.0 degrees (the previously observed angle for this sequence was 41.4 degrees) as a right-handed X. No metal cations were observed; the crystals were grown in the presence of only group I counter-cations.
[[Category: Teixeira SCM]]
 
[[Category: Thorpe JH]]
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUC OCA].  
 
==Reference==
Structural characterization of a new crystal form of the four-way Holliday junction formed by the DNA sequence d(CCGGTACCGG)2: sequence versus lattice?, Thorpe JH, Teixeira SC, Gale BC, Cardin CJ, Acta Crystallogr D Biol Crystallogr. 2002 Mar;58(Pt 3):567-9. Epub 2002, Feb 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11856858 11856858]
[[Category: Cardin, C J.]]
[[Category: Gale, B C.]]
[[Category: Teixeira, S C.M.]]
[[Category: Thorpe, J H.]]
[[Category: Holliday junction]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 21:56:05 2008''

Latest revision as of 07:42, 7 February 2024

Crystal Structure Analysis of a Holliday Junction Formed by CCGGTACCGG

1juc, resolution 2.35Å

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