1k44: Difference between revisions

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[[Image:1k44.gif|left|200px]]


{{Structure
==Mycobacterium tuberculosis Nucleoside Diphosphate Kinase==
|PDB= 1k44 |SIZE=350|CAPTION= <scene name='initialview01'>1k44</scene>, resolution 2.6&Aring;
<StructureSection load='1k44' size='340' side='right'caption='[[1k44]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1k44]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K44 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k44 OCA], [https://pdbe.org/1k44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k44 RCSB], [https://www.ebi.ac.uk/pdbsum/1k44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k44 ProSAT], [https://www.topsan.org/Proteins/TBSGC/1k44 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=[[1nue|1NUE]]
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k44 OCA], [http://www.ebi.ac.uk/pdbsum/1k44 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1k44 RCSB]</span>
[https://www.uniprot.org/uniprot/NDK_MYCTU NDK_MYCTU] Major role in the synthesis of nucleoside triphosphates other than ATP.[HAMAP-Rule:MF_00451]
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k44_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k44 ConSurf].
<div style="clear:both"></div>


'''Mycobacterium tuberculosis Nucleoside Diphosphate Kinase'''
==See Also==
 
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1K44 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K44 OCA].
[[Category: Large Structures]]
 
==Reference==
X-ray structure of Mycobacterium tuberculosis nucleoside diphosphate kinase., Chen Y, Morera S, Mocan J, Lascu I, Janin J, Proteins. 2002 Jun 1;47(4):556-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12001234 12001234]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Chen Y]]
[[Category: Single protein]]
[[Category: Janin J]]
[[Category: Chen, Y.]]
[[Category: Lascu I]]
[[Category: Janin, J.]]
[[Category: Morera S]]
[[Category: Lascu, I.]]
[[Category: Morera, S.]]
[[Category: nucleoside diphosphate]]
[[Category: nucleoside triphosphate]]
 
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Retrieved from "https://proteopedia.org/1k44"