7al9: Difference between revisions
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==human GTP cyclohydrolase I feedback regulatory protein (GFRP) in complex with phenylalanine== | |||
<StructureSection load='7al9' size='340' side='right'caption='[[7al9]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7al9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AL9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.745Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7al9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7al9 OCA], [https://pdbe.org/7al9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7al9 RCSB], [https://www.ebi.ac.uk/pdbsum/7al9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7al9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GFRP_HUMAN GFRP_HUMAN] Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.<ref>PMID:16778797</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ebenhoch R]] | |||
[[Category: Nar H]] | |||
Latest revision as of 07:51, 7 February 2024
human GTP cyclohydrolase I feedback regulatory protein (GFRP) in complex with phenylalanine
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