1kkb: Difference between revisions

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{{Seed}}
[[Image:1kkb.png|left|200px]]


<!--
==Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin==
The line below this paragraph, containing "STRUCTURE_1kkb", creates the "Structure Box" on the page.
<StructureSection load='1kkb' size='340' side='right'caption='[[1kkb]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1kkb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KKB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HDA:HADACIDIN'>HDA</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
{{STRUCTURE_1kkb| PDB=1kkb |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kkb OCA], [https://pdbe.org/1kkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kkb RCSB], [https://www.ebi.ac.uk/pdbsum/1kkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kkb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PURA_ECOLI PURA_ECOLI] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).[HAMAP-Rule:MF_00011]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/1kkb_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kkb ConSurf].
<div style="clear:both"></div>


===Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin===
==See Also==
 
*[[Adenylosuccinate synthetase 3D structures|Adenylosuccinate synthetase 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11741996}}, adds the Publication Abstract to the page
[[Category: Escherichia coli K-12]]
(as it appears on PubMed at http://www.pubmed.gov), where 11741996 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Fromm HJ]]
{{ABSTRACT_PUBMED_11741996}}
[[Category: Honzatko RB]]
 
[[Category: Hou Z]]
==About this Structure==
[[Category: Wang W]]
1KKB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KKB OCA].
 
==Reference==
<ref group="xtra">PMID:11741996</ref><references group="xtra"/>
[[Category: Adenylosuccinate synthase]]
[[Category: Escherichia coli]]
[[Category: Fromm, H J.]]
[[Category: Honzatko, R B.]]
[[Category: Hou, Z.]]
[[Category: Wang, W.]]
[[Category: Biosynthesis]]
[[Category: Gtp-hydrolysing enzyme]]
[[Category: Induced fit]]
[[Category: Ligase]]
[[Category: Purine nucleotide]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:21:05 2009''

Latest revision as of 07:25, 14 February 2024

Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin

1kkb, resolution 2.60Å

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