1mi3: Difference between revisions

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[[Image:1mi3.png|left|200px]]


{{STRUCTURE_1mi3|  PDB=1mi3  |  SCENE=  }}
==1.8 Angstrom structure of xylose reductase from Candida tenuis in complex with NAD==
 
<StructureSection load='1mi3' size='340' side='right'caption='[[1mi3]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===1.8 Angstrom structure of xylose reductase from Candida tenuis in complex with NADH===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1mi3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Yamadazyma_tenuis Yamadazyma tenuis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MI3 FirstGlance]. <br>
{{ABSTRACT_PUBMED_12733986}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mi3 OCA], [https://pdbe.org/1mi3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mi3 RCSB], [https://www.ebi.ac.uk/pdbsum/1mi3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mi3 ProSAT]</span></td></tr>
[[1mi3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_tenuis Candida tenuis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MI3 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/XYL1_CANTE XYL1_CANTE] Reduces D-xylose into xylitol. Has a preference for NADPH, but can also utilize NADH as cosubstrate.
<ref group="xtra">PMID:012733986</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Aldehyde reductase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Candida tenuis]]
Check<jmol>
[[Category: Kavanagh, K L.]]
  <jmolCheckbox>
[[Category: Klimacek, M.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mi3_consurf.spt"</scriptWhenChecked>
[[Category: Nidetzky, B.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Wilson, D K.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Aldo-keto reductase]]
  </jmolCheckbox>
[[Category: Beta-alpha barrel]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mi3 ConSurf].
[[Category: Dimer]]
<div style="clear:both"></div>
[[Category: Oxidoreductase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Yamadazyma tenuis]]
[[Category: Kavanagh KL]]
[[Category: Klimacek M]]
[[Category: Nidetzky B]]
[[Category: Wilson DK]]

Latest revision as of 07:44, 14 February 2024

1.8 Angstrom structure of xylose reductase from Candida tenuis in complex with NAD

1mi3, resolution 1.80Å

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