1mlx: Difference between revisions

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{{Seed}}
[[Image:1mlx.png|left|200px]]


<!--
==Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex==
The line below this paragraph, containing "STRUCTURE_1mlx", creates the "Structure Box" on the page.
<StructureSection load='1mlx' size='340' side='right'caption='[[1mlx]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mlx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MLX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SMT:2-[(METHYLTHIO)ETHYLOXY]-THYMIDINE-5-MONOPHOSPHATE'>SMT</scene></td></tr>
{{STRUCTURE_1mlx|  PDB=1mlx  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mlx OCA], [https://pdbe.org/1mlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mlx RCSB], [https://www.ebi.ac.uk/pdbsum/1mlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mlx ProSAT]</span></td></tr>
 
</table>
===Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex===
__TOC__
 
</StructureSection>
 
[[Category: Large Structures]]
<!--
[[Category: Egli M]]
The line below this paragraph, {{ABSTRACT_PUBMED_12269806}}, adds the Publication Abstract to the page
[[Category: Fraser AS]]
(as it appears on PubMed at http://www.pubmed.gov), where 12269806 is the PubMed ID number.
[[Category: Kawasaki AM]]
-->
[[Category: Leeds JM]]
{{ABSTRACT_PUBMED_12269806}}
[[Category: Lesnik EA]]
 
[[Category: Manoharan M]]
==About this Structure==
[[Category: Prakash TP]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MLX OCA].  
[[Category: Sioufi N]]
 
[[Category: Teplova M]]
==Reference==
2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA., Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M, Biochemistry. 2002 Oct 1;41(39):11642-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12269806 12269806]
[[Category: Egli, M.]]
[[Category: Fraser, A S.]]
[[Category: Kawasaki, A M.]]
[[Category: Leeds, J M.]]
[[Category: Lesnik, E A.]]
[[Category: Manoharan, M.]]
[[Category: Prakash, T P.]]
[[Category: Sioufi, N.]]
[[Category: Teplova, M.]]
[[Category: A-form]]
[[Category: Antisense modification]]
[[Category: Dna]]
[[Category: Double helix]]
[[Category: High resolution structure]]
[[Category: Hydration]]
[[Category: Nuclease resistance]]
[[Category: Nucleic acid analogue]]
[[Category: Protein binding affinity]]
[[Category: Rna affinity]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 00:17:52 2008''

Latest revision as of 07:45, 14 February 2024

Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex

1mlx, resolution 1.25Å

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