1pbk: Difference between revisions

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<StructureSection load='1pbk' size='340' side='right'caption='[[1pbk]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1pbk' size='340' side='right'caption='[[1pbk]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1pbk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PBK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1PBK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1pbk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PBK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RAP:RAPAMYCIN+IMMUNOSUPPRESSANT+DRUG'>RAP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN HIPPOCAMPAL CDNA LIBRARY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RAP:RAPAMYCIN+IMMUNOSUPPRESSANT+DRUG'>RAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1pbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pbk OCA], [http://pdbe.org/1pbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pbk RCSB], [http://www.ebi.ac.uk/pdbsum/1pbk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1pbk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pbk OCA], [https://pdbe.org/1pbk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pbk RCSB], [https://www.ebi.ac.uk/pdbsum/1pbk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pbk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FKBP3_HUMAN FKBP3_HUMAN] FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Clardy, J]]
[[Category: Clardy J]]
[[Category: Hung, D T]]
[[Category: Hung DT]]
[[Category: Liang, J]]
[[Category: Liang J]]
[[Category: Schreiber, S L]]
[[Category: Schreiber SL]]
[[Category: Fkbp12 homologous domain of hfkbp25]]
[[Category: Isomerase]]
Retrieved from "https://proteopedia.org/1pbk"