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[[Image:1pdn.png|left|200px]]


{{STRUCTURE_1pdn|  PDB=1pdn  |  SCENE=  }}
==CRYSTAL STRUCTURE OF A PAIRED DOMAIN-DNA COMPLEX AT 2.5 ANGSTROMS RESOLUTION REVEALS STRUCTURAL BASIS FOR PAX DEVELOPMENTAL MUTATIONS==
 
<StructureSection load='1pdn' size='340' side='right'caption='[[1pdn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===CRYSTAL STRUCTURE OF A PAIRED DOMAIN-DNA COMPLEX AT 2.5 ANGSTROMS RESOLUTION REVEALS STRUCTURAL BASIS FOR PAX DEVELOPMENTAL MUTATIONS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1pdn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PDN FirstGlance]. <br>
{{ABSTRACT_PUBMED_7867071}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pdn OCA], [https://pdbe.org/1pdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pdn RCSB], [https://www.ebi.ac.uk/pdbsum/1pdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdn ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1pdn]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDN OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/PRD_DROME PRD_DROME] Pair-rule protein expressed in a segmentally repeating pattern to define the polarity of embryonic segments. Capable of sequence-specific DNA-binding.
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:007867071</ref><ref group="xtra">PMID:011258480</ref><ref group="xtra">PMID:015048824</ref><ref group="xtra">PMID:017397256</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/1pdn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pdn ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Desplan, C.]]
[[Category: Large Structures]]
[[Category: Jun, S.]]
[[Category: Desplan C]]
[[Category: Pabo, C O.]]
[[Category: Jun S]]
[[Category: Rould, M A.]]
[[Category: Pabo CO]]
[[Category: Xu, W.]]
[[Category: Rould MA]]
[[Category: Dna-binding protein]]
[[Category: Xu W]]
[[Category: Double helix]]
[[Category: Gene regulation-dna complex]]
[[Category: Paired domain]]
[[Category: Pax]]
[[Category: Prd]]
[[Category: Protein-dna complex]]
Retrieved from "https://proteopedia.org/1pdn"