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[[Image:1pry.png|left|200px]]


{{STRUCTURE_1pry|  PDB=1pry  |  SCENE=  }}
==Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)==
 
<StructureSection load='1pry' size='340' side='right'caption='[[1pry]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
===Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1pry]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PRY FirstGlance]. <br>
{{ABSTRACT_PUBMED_14975761}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pry OCA], [https://pdbe.org/1pry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pry RCSB], [https://www.ebi.ac.uk/pdbsum/1pry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pry ProSAT], [https://www.topsan.org/Proteins/SECSG/1pry TOPSAN]</span></td></tr>
==About this Structure==
</table>
[[1pry]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRY OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/FLPA_PYRFU FLPA_PYRFU] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).[HAMAP-Rule:MF_00351]
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:014975761</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Pyrococcus furiosus]]
Check<jmol>
[[Category: Deng, L.]]
  <jmolCheckbox>
[[Category: Liu, Z J.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/1pry_consurf.spt"</scriptWhenChecked>
[[Category: Rose, J P.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Starostina, N G.]]
  </jmolCheckbox>
[[Category: Terns, M P.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pry ConSurf].
[[Category: Terns, R M.]]
<div style="clear:both"></div>
[[Category: Wang, B C.]]
__TOC__
[[Category: Fibrillarin]]
</StructureSection>
[[Category: Methylation]]
[[Category: Large Structures]]
[[Category: Pfu-65527]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
[[Category: Ribosomal rna processing]]
[[Category: Deng L]]
[[Category: Secsg]]
[[Category: Liu Z-J]]
[[Category: Snornp]]
[[Category: Rose JP]]
[[Category: Southeast collaboratory for structural genomic]]
[[Category: Starostina NG]]
[[Category: Structural genomic]]
[[Category: Terns MP]]
[[Category: Transferase]]
[[Category: Terns RM]]
[[Category: Wang B-C]]
Retrieved from "https://proteopedia.org/1pry"