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[[Image:1tic.png|left|200px]]


{{STRUCTURE_1tic|  PDB=1tic  |  SCENE=  }}
==CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR==
 
<StructureSection load='1tic' size='340' side='right'caption='[[1tic]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
===CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1tic]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizopus_arrhizus Rhizopus arrhizus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TIC FirstGlance]. <br>
{{ABSTRACT_PUBMED_8014587}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tic OCA], [https://pdbe.org/1tic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tic RCSB], [https://www.ebi.ac.uk/pdbsum/1tic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tic ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1tic]] is a 2 chain structure of [[Lipase]] with sequence from [http://en.wikipedia.org/wiki/Rhizopus_oryzae Rhizopus oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TIC OCA].  
== Function ==
[https://www.uniprot.org/uniprot/LIP_RHIOR LIP_RHIOR] Hydrolyzes ester bonds of triglycerides as well as of their derived partial glycerides with a strong 1,3-positional specificity.<ref>PMID:11506890</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ti/1tic_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tic ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Lipase|Lipase]]
*[[Lipase 3D Structures|Lipase 3D Structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:008014587</ref><references group="xtra"/>
__TOC__
[[Category: Rhizopus oryzae]]
</StructureSection>
[[Category: Triacylglycerol lipase]]
[[Category: Large Structures]]
[[Category: Derewenda, U.]]
[[Category: Rhizopus arrhizus]]
[[Category: Derewenda, Z S.]]
[[Category: Derewenda U]]
[[Category: Green, R.]]
[[Category: Derewenda ZS]]
[[Category: Haas, M J.]]
[[Category: Green R]]
[[Category: Joerger, R.]]
[[Category: Haas MJ]]
[[Category: Swenson, L.]]
[[Category: Joerger R]]
[[Category: Swenson L]]
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