1z2c: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1z2c.png|left|200px]]


<!--
==Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP==
The line below this paragraph, containing "STRUCTURE_1z2c", creates the "Structure Box" on the page.
<StructureSection load='1z2c' size='340' side='right'caption='[[1z2c]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1z2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z2C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1z2c| PDB=1z2c |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2c OCA], [https://pdbe.org/1z2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z2c RCSB], [https://www.ebi.ac.uk/pdbsum/1z2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z2c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RHOC_HUMAN RHOC_HUMAN] Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.<ref>PMID:16236794</ref> <ref>PMID:20974804</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z2c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z2c ConSurf].
<div style="clear:both"></div>


===Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP===
==See Also==
 
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
 
*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
<!--
== References ==
The line below this paragraph, {{ABSTRACT_PUBMED_15864301}}, adds the Publication Abstract to the page
<references/>
(as it appears on PubMed at http://www.pubmed.gov), where 15864301 is the PubMed ID number.
__TOC__
-->
</StructureSection>
{{ABSTRACT_PUBMED_15864301}}
 
==About this Structure==
1Z2C is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2C OCA].
 
==Reference==
Structural and mechanistic insights into the interaction between Rho and mammalian Dia., Rose R, Weyand M, Lammers M, Ishizaki T, Ahmadian MR, Wittinghofer A, Nature. 2005 May 26;435(7041):513-8. Epub 2005 May 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15864301 15864301]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Ahmadian MR]]
[[Category: Ahmadian, M R.]]
[[Category: Ishizaki T]]
[[Category: Ishizaki, T.]]
[[Category: Lammers M]]
[[Category: Lammers, M.]]
[[Category: Rose R]]
[[Category: Rose, R.]]
[[Category: Weyand M]]
[[Category: Weyand, M.]]
[[Category: Wittinghofer A]]
[[Category: Wittinghofer, A.]]
[[Category: Armadillo repeat]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:22:51 2008''

Latest revision as of 09:02, 14 February 2024

Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP

1z2c, resolution 3.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1z2c&oldid=4057045"