2gh7: Difference between revisions

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{{Seed}}
[[Image:2gh7.png|left|200px]]


<!--
==Epi-biotin complex with core streptavidin==
The line below this paragraph, containing "STRUCTURE_2gh7", creates the "Structure Box" on the page.
<StructureSection load='2gh7' size='340' side='right'caption='[[2gh7]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gh7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GH7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_2gh7| PDB=2gh7 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gh7 OCA], [https://pdbe.org/2gh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gh7 RCSB], [https://www.ebi.ac.uk/pdbsum/2gh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gh7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gh/2gh7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gh7 ConSurf].
<div style="clear:both"></div>


===Epi-biotin complex with core streptavidin===
==See Also==
 
*[[Avidin 3D structures|Avidin 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_16699183}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 16699183 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16699183}}
 
==About this Structure==
2GH7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GH7 OCA].
 
==Reference==
The high-resolution structure of (+)-epi-biotin bound to streptavidin., Le Trong I, Aubert DG, Thomas NR, Stenkamp RE, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):576-81. Epub 2006, May 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16699183 16699183]
[[Category: Single protein]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
[[Category: Aubert, D G.L.]]
[[Category: Aubert DGL]]
[[Category: Stenkamp, R E.]]
[[Category: Le Trong I]]
[[Category: Thomas, N R.]]
[[Category: Stenkamp RE]]
[[Category: Trong, I Le.]]
[[Category: Thomas NR]]
[[Category: Biotin]]
[[Category: Protein/ligand interaction]]
[[Category: Streptavidin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:16:01 2008''

Latest revision as of 09:27, 14 February 2024

Epi-biotin complex with core streptavidin

2gh7, resolution 1.00Å

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