2gvx: Difference between revisions

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{{Seed}}
[[Image:2gvx.png|left|200px]]


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==Structure of diisopropyl fluorophosphatase (DFPase), mutant D229N / N175D==
The line below this paragraph, containing "STRUCTURE_2gvx", creates the "Structure Box" on the page.
<StructureSection load='2gvx' size='340' side='right'caption='[[2gvx]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gvx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2gvx|  PDB=2gvx  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvx OCA], [https://pdbe.org/2gvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gvx RCSB], [https://www.ebi.ac.uk/pdbsum/2gvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvx ProSAT]</span></td></tr>
 
</table>
===Structure of diisopropyl fluorophosphatase (DFPase), mutant D229N / N175D===
== Function ==
 
[https://www.uniprot.org/uniprot/DFPA_LOLVU DFPA_LOLVU] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).<ref>PMID:15966726</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gvx_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_17002369}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2GVX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVX OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gvx ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism., Blum MM, Lohr F, Richardt A, Ruterjans H, Chen JC, J Am Chem Soc. 2006 Oct 4;128(39):12750-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17002369 17002369]
<references/>
[[Category: Diisopropyl-fluorophosphatase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Loligo vulgaris]]
[[Category: Loligo vulgaris]]
[[Category: Single protein]]
[[Category: Blum M-M]]
[[Category: Blum, M M.]]
[[Category: Chen JC-H]]
[[Category: Chen, J C.H.]]
[[Category: Lohr F]]
[[Category: Lohr, F.]]
[[Category: Richardt A]]
[[Category: Richardt, A.]]
[[Category: Ruterjans H]]
[[Category: Ruterjans, H.]]
[[Category: Beta-propeller]]
[[Category: Phosphotriesterase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:47:51 2008''
Retrieved from "https://proteopedia.org/2gvx"