2hb2: Difference between revisions

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{{Seed}}
[[Image:2hb2.png|left|200px]]


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==Structure of HIV protease 6X mutant in apo form==
The line below this paragraph, containing "STRUCTURE_2hb2", creates the "Structure Box" on the page.
<StructureSection load='2hb2' size='340' side='right'caption='[[2hb2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hb2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HB2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hb2 OCA], [https://pdbe.org/2hb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hb2 RCSB], [https://www.ebi.ac.uk/pdbsum/2hb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hb2 ProSAT]</span></td></tr>
{{STRUCTURE_2hb2|  PDB=2hb2 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9E3M8_9HIV1 Q9E3M8_9HIV1]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hb/2hb2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hb2 ConSurf].
<div style="clear:both"></div>


===Structure of HIV protease 6X mutant in apo form===
==See Also==
 
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17642513}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17642513 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17642513}}
 
==About this Structure==
2HB2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HB2 OCA].
 
==Reference==
Conformational flexibility in the flap domains of ligand-free HIV protease., Heaslet H, Rosenfeld R, Giffin M, Lin YC, Tam K, Torbett BE, Elder JH, McRee DE, Stout CD, Acta Crystallogr D Biol Crystallogr. 2007 Aug;63(Pt 8):866-75. Epub 2007, Jul 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17642513 17642513]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Elder, J H.]]
[[Category: Elder JH]]
[[Category: Heaslet, H.]]
[[Category: Heaslet H]]
[[Category: Stout, C D.]]
[[Category: Stout CD]]
[[Category: Tam, K.]]
[[Category: Tam K]]
[[Category: Aspartyl]]
[[Category: Hiv]]
[[Category: Protease]]
[[Category: Retrovirus]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:07:27 2008''

Latest revision as of 09:31, 14 February 2024

Structure of HIV protease 6X mutant in apo form

2hb2, resolution 2.30Å

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